Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice

Behavioral despair in mice: a primary screening test for antidepressants.

Porsolt Rd, Aurélie Bertin, M Jalfre · PubMed · 1977 · 3.3K citations

Medicine, Pharmacology, Psychiatry +17

Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines

Jacqueline N. Crawley, Frederick K. Goodwin · Pharmacology Biochemistry and Behavior · 1980 · 1.4K citations

Medicine, Behavioral Sciences, Pharmacology +13

Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity.

Jay Dinerman, Ted M. Dawson, Michael J. Schell et al. · Proceedings of the National Academy of Sciences · 1994 · 651 citations

Life Sciences, Neurobiology, Neuroscience +13

Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase

Randy J. Nelson, Gregory E. Demas, Paul L. Huang et al. · Nature · 1995 · 603 citations

Life Sciences, Neurobiology, Neuroscience +11

Inhibition of nitric oxide synthesis by methylene blue

Bernd Mayer, Friedrich Brünner, Kurt Schmidt · Biochemical Pharmacology · 1993 · 536 citations

Natural Sciences, Chemistry, Pharmacology +6