Rumphellatin D, a Novel Chlorinated Caryophyllane from Gorgonian Coral <i>Rumphella antipathies</i>

Abstract

Abstract The first chloride-containing caryophyllane-type sesquiterpenoid, designated as rumphellatin D (1), was isolated from gorgonian coral Rumphella antipathies. The structure of 1 was established by spectral-data analysis. Rumphellatin D (1) showed moderate inhibitory effects on elastase release by human neutrophils.