Concepedia

Publication | Open Access

FLT3 activation cooperates with MLL-AF4 fusion protein to abrogate the hematopoietic specification of human ESCs

DOIFull Paper Access

40

Citations

40

References

2013

Year

Clara Bueno, Verónica Ayllón, Rosa Montes, Óscar Navarro-Montero, Verónica Ramos–Mejía, Pedro J. Real, Damià Romero–Moya, Marcos J. Araúzo‐Bravo, Pablo Menéndez
Blood

Abstract

Key Points FLT3 activation cooperates with the MLL-AF4 fusion gene to fully abolish blood formation from hESCs. FLT3 activation does not cooperate with the MLL-AF4 fusion oncogene to transform hESCs or hESC-derived hematopoietic progeny.

References

YearCitations

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