Insulin prophylaxis in individuals at high risk of type 1 diabetes

A Randomized Trial of Intensive Insulin Therapy in Newly Diagnosed Insulin-Dependent Diabetes Mellitus

Shirish C. Shah, John I. Malone, Norma E. Simpson · New England Journal of Medicine · 1989 · 319 citations

Medicine, Endocrinology, Internal Medicine +17

Insulitis and Diabetes in NOD Mice Reduced by Prophylactic Insulin Therapy

Mark A. Atkinson, Noel K. Maclaren, Roberto Luchetta · Diabetes · 1990 · 294 citations

Medicine, Endocrinology, Immunology +8

Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals

C. F. Gotfredsen, Karsten Buschard, Erik Frandsen · Diabetologia · 1985 · 208 citations · Full text

Medicine, Animal Sciences, Endocrinology +10

Competitive Insulin Autoantibody Assay: Prospective Evaluation of Subjects at High Risk for Development of Type I Diabetes Mellitus

Pnina Vardi, Sérgio Atala Dib, Marilyn Tuttleman et al. · Diabetes · 1987 · 181 citations

Life Sciences, Endocrinology, Immunology +14

Interaction of β-Cell Activity and IL-1 Concentration and Exposure Time in Isolated Rat Islets of Langerhans

Jerry P. Palmer, Steffen Helqvist, Giatgen A. Spinas et al. · Diabetes · 1989 · 130 citations

Life Sciences, Cell Biology, Endocrinology +15