Anaesthesia · 2002 · 14 citations · 21 references
MedicineHematologyPatient SafetySepsisTransfusion MedicineBlood Transfusion ManagementBlood Transfusion SafetyPlatelet TransfusionRed Blood Cell TransfusionTransfusion SupportTransfusion TherapyAllogeneic TransfusionBlood By-productsCritical Care Transfusion PracticeLactate AcidosisPlatelet Transfusion TherapyRed Blood Cell Transfusion SafetyTransfusion IndicationsTransfusion Threshold Assessment
This study aimed to examine the attitudes of intensivists and haematologists to the use of blood and blood products using a scenario-based postal questionnaire. One hundred and sixty-two intensivists and 77 haematologists responded to the survey. In four scenarios, the baseline haemoglobin thresholds for red cell transfusion ranged from 6 to 12 g.dl(-1). There was significant variation between scenarios (p <0.005). Increasing age, high Acute Physiology and Chronic Health Status II score, surgery, acute respiratory distress syndrome, septic shock and lactic acidosis significantly (p <0.005) modified the transfusion threshold. There were greater variations in the baseline threshold for platelet transfusion. The majority of respondents (72.3%) selected a baseline haemoglobin threshold between 9 and 10 g.dl(-1). The thresholds for platelet transfusion were far less consistent.
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William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1985 · 13.7K citations
Medicine, Internal Medicine, Clinical Classification Systems +16