XERODERMA PIGMENTOSUM

Abstract

The patient whose case of xeroderma pigmentosum is reported in this paper presented an unusual clinical picture, and the diagnosis was definitely established only after histopathologic studies had been made. Certain histopathologic features which we consider diagnostic of the disease will be emphasized. Finally, some of the clinical and histopathologic features in the case will be considered briefly in connection with certain etiologic concepts regarding the disease. The clinical picture of the disease in its various stages, together with a review of the literature, is adequately given in modern textbooks of dermatology and will not be considered further.¹ REPORT OF A CASE <i>History</i>.—A widow, aged 32, came to the Mayo Clinic in September, 1929, because of dysmenorrhea. She was born in Colorado, and was of Scotch, Irish and German descent. There was no consanguinity of the parents, and they were living and well. Two brothers had died