Voltammetric Determination of Nicotine at Poly(4‐Amino‐3‐Hydroxynaphthalene Sulfonic Acid)‐Modified Glassy Carbon Electrode

Abstract

Abstract A poly(4‐amino‐3‐hydroxynaphthalene sulfonic acid)‐modified glassy carbon electrode was developed for the voltammetric determination of nicotine. An oxidation signal at lower potential with higher current was obtained for nicotine at the polymer‐modified electrode compared to bare glassy carbon electrode suggesting the electrocatalytic effect of the polymer film. Under optimum conditions, square wave voltammetry of nicotine showed oxidation at +884 mV (vs. SCE) in phosphate buffer solution pH 7.5. The calibration curve was linear over the range 1.0 to 200.0 µM ( R 2 =0.9987) concentration of nicotine with a detection limit ( S / N =3) of 8.66×10 −7 mol L −1 . Application of the proposed method to cigarette tobacco samples gave acceptable recovery results of 90.7 % to 107.2 %.