Concepedia

Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle

Louis J. Ignarro, Margaret A. Bush, Georgette M. Buga, K S Wood, Jon M. Fukuto, Jacob Rajfer

Biochemical and Biophysical Research Communications · 1990 · 849 citations · 12 references

DOI

Concepts

References

12

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

, , +15

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

L J Ignarro, Howard Lippton, Jo C. W. Edwards et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 1.6K citations

, , +6

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

Richard Palmer, Daryl D. Rees, David Ashton et al. · Biochemical and Biophysical Research Communications · 1988 · 1.4K citations

, , +9

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

Louis J. Ignarro, R E Byrns, Georgette M. Buga et al. · Circulation Research · 1987 · 1.2K citations

, , +8

Impaired Neurogenic and Endothelium-Mediated Relaxation of Penile Smooth Muscle from Diabetic Men with Impotence

I Sáenz de Tejada, Irwin Goldstein, Kazem M. Azadzoi et al. · New England Journal of Medicine · 1989 · 959 citations

, , +14