A New Substrate for the Biginelli Cyclocondensation: Direct Preparation of 5-Unsubstituted 3,4-Dihydropyrimidin-2(1<i>H</i>)-ones from a β-Keto Carboxylic Acid

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTA New Substrate for the Biginelli Cyclocondensation: Direct Preparation of 5-Unsubstituted 3,4-Dihydropyrimidin-2(1H)-ones from a β-Keto Carboxylic AcidJacqueline C. Bussolari and Patricia A. McDonnellView Author Information The R.W. Johnson Pharmaceutical Research Institute, 1000 Route 202, Raritan, New Jersey 08869 [email protected]Cite this: J. Org. Chem. 2000, 65, 20, 6777–6779Publication Date (Web):September 7, 2000Publication History Received8 May 2000Published online7 September 2000Published inissue 1 October 2000https://doi.org/10.1021/jo005512aCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views1008Altmetric-Citations73LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (49 KB) Get e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Chemical reactions,Cyclization,Organic acids,Organic compounds,Organic reactions Get e-Alerts