Concepedia

Slow Wave Sleep Induced by GABA Agonist Tiagabine Fails to Benefit Memory Consolidation

Gordon B. Feld, Ines Wilhelm, Ying Ma, Sabine Groch, Ferdinand Binkofski, Matthias Mölle, Jan Born

SLEEP · 2013 · 75 citations · 45 references

DOIFull text

Open access

Abstract

Our data show that increasing slow wave sleep with tiagabine does not improve memory consolidation. Possibly this is due to functional differences from normal slow wave sleep, i.e., the concurrent suppressive influence of tiagabine on phase-locked spindle activity.

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