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A comparison of aroclor 1254-induced and uninduced rat liver microsomes to human liver microsomes in phenytoin O-deethylation, coumarin 7-hydroxylation, tolbutamide 4-hydroxylation, S-mephenytoin 4′-hydroxylation, chloroxazone 6-hydroxylation and testosterone 6β-hydroxylation

Molecular PharmacologyHepatologyBiochemistryMedicineLiver PhysiologyCoumarin 7-HydroxylationToxicologyHuman Liver MicrosomesPhenytoin O-deethylationHepatotoxicityExperimental ToxicologyPharmacologyDrug-induced Liver InjuryToxicological Mechanism