Inhibitors of apoptosis in testicular germ cells: Synthesis and biological evaluation of some novel IBTs bearing sulfonamide moiety

Thymocyte apoptosis induced by p53-dependent and independent pathways

Alan R. Clarke, Colin A. Purdie, David J. Harrison et al. · Nature · 1993 · 2.3K citations

Life Sciences, Cell Biology, Molecular Genetics +14

A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy

Pavel G. Komarov, Elena A. Komarova, Roman V. Kondratov et al. · Science · 1999 · 1.3K citations

Medicine, Oncology, Pharmacology +17

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide

Carsten Culmsee, Xiaoxiang Zhu, Qian‐sheng Yu et al. · Journal of Neurochemistry · 2001 · 316 citations

Life Sciences, Neuroscience, Pharmacology +17

Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7 Inhibit Apoptosis and Maintain Cell Functionality

Dennis Lee, Scott A. Long, Jerry L. Adams et al. · Journal of Biological Chemistry · 2000 · 234 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +8

Activation of the Abelson tyrosine kinase activity is associated with suppression of apoptosis in hemopoietic cells.

Caroline A. Evans, P. Jane Owen‐Lynch, Anthony D. Whetton et al. · PubMed · 1993 · 154 citations

Life Sciences, Cell Biology, Molecular Biology +13