Resuscitation of critically ill patients based on the results of gastric tonometry: A prospective, randomized, controlled trial

Abstract

The routine use of treatment titrated against pHi in the management of critically ill patients cannot be supported. Failure to improve outcome may be caused by an inability to produce a clinically significant change in pHi or because pHi is simply a marker of disease rather than a factor in the pathogenesis of multiorgan failure.