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Pi Phenotypes in Greeks
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1974
Year
GeneticsGenetic EpidemiologyHuman PolymorphismGene FrequenciesMolecular GeneticsGenetic AnalysisGreek PopulationGenotype-phenotype AssociationBiostatisticsPublic HealthStatistical GeneticsGenetic VariationPi PhenotypesPopulation GeneticsBiologyAllelic VariantPi Serum TypesMedicineMendelian Inheritance
Pi serum types were determined by starch gel electrophoresis in 504 unrelated healthy adults representative of the Greek population. Gene frequencies were as follows: PiM, 0.960; PiS, 0.028; PiZ, 0.002; PiF, 0.006; and PiV, 0.002. No significant heterogeneity was found in this material, and distribution of Pi phenotypes is in good agreement with the Hardy-Weinberg equilibrium. PiI, PiW, PiX, and PiP alleles were not found.