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THE EFFECT OF ASPIRIN ON THE PULMONARY EXTRACTION OF PGF<sub>2α</sub>, AND CARDIOVASCULAR RESPONSE TO PGF<sub>2α</sub>
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0
References
1973
Year
AsthmaLung InflammationCardiovascular PharmacologyPulmonary PharmacologyPublic HealthCardiologyPulmonary CirculationPulmonary MedicinePharmacologySummary AspirinPulmonary DiseasePulmonary Vascular DiseasePulmonary ExtractionPulmonary Arterial HypertensionCardiovascular DiseasePhysiologyPulmonary PhysiologyProstaglandin F 2αMedicineAnesthesiology
Summary Aspirin significantly inhibited the pulmonary extraction of prostaglandin F 2α . This effect of aspirin on the pulmonary circulation was associated with a significant change in the cardiovascular response to intravenous infusions of prostaglandin F 2α but no change in the response to arterial infusions. Before aspirin intravenous infusions of prostaglandin F 2α caused a significant fall in central venous pressure and a rise in cardiac output, while after aspirin prostaglandin F. 2α caused a rise in central venous pressure and a fall in cardiac output.