Rabbits immunized against b6 allotype express similar anti‐b6 idiotopes

Abstract

Similar idiotopes are detected on anti-allotypic antibodies synthesized by all rabbits immunized against the b6 allotype. The expression of similar idiotypes on anti-b6 antibodies has been found in rabbits of all VHa allotypic types thus far studies. For their expression, these idiotypes require the interaction between VL and VH domains.