Synthesis and cytotoxic, anti-inflammatory, and anti-oxidant activities of 2′,5′-dialkoxylchalcones as cancer chemopreventive agents

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

Aihao Ding, Carl Nathan, Dennis J. Stuehr · The Journal of Immunology · 1988 · 2.8K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Activation of microglial cells by β-amyloid protein and interferon-γ

Lucia Meda, Marco A. Cassatella, Györgyi I. Szendrei et al. · Nature · 1995 · 1.3K citations

Life Sciences, Immunology, Neuroscience +14

Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo

Christoph Thiemermann, John R. Vane · European Journal of Pharmacology · 1990 · 528 citations

Life Sciences, Microbiology, Pharmacology +7

Synthetic chalcones as potential anti-inflammatory and cancer chemopreventive agents

Shen‐Jeu Won, Cheng‐Tsung Liu, Lo‐Ti Tsao et al. · European Journal of Medicinal Chemistry · 2004 · 283 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Synthesis and biological evaluation of chalcones and their derived pyrazoles as potential cytotoxic agents

Bilal A. Bhat, K.L. Dhar, S. C. Puri et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 274 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11