BMJ · 1974 · 58 citations · 28 references
MedicineCardiologyInternal MedicineCardiovascular PharmacotherapyClinical CardiologyElectrophysiologyAtrial ElectrophysiologyAtrial FibrillationCardiac ArrhythmiasCardiac MedicationsCardiac PacingPacemaker CareAnticoagulation In CardiomyopathyCardiac PacemakersCardiovascular SurgeryDevice EmbolizationIntracardiac PacingPacemaker ComplicationsPacemaker Malfunction
Out of a pacemaker clinic population of 182 patients 21 (11.5%) were found to have the sick sinus syndrome. Their ages ranged from 30 to 80 years and averaged 62. Ischaemic heart disease was more commonly an aetiological factor than in patients with chronic atrioventricular heart block. Other aetiologies were familial cardiomyopathy, postcardiac surgery, and dystrophia myotonica.Cardioversion before pacemaker insertion was a hazardous procedure. After insertion the occurrence of tachycardias and the need for drug therapy were reduced. One patient no longer required a pacemaker once atrial fibrillation became established.A high incidence of cerebral embolization was observed and the use of anticoagulant drugs therefore merits serious consideration.Failure of inhibition of demand-type pacemakers occurred in two patients. Two patients who exhibited competition with fixed-rate pacemakers died. Two patients were treated with electrodes surgically implanted on the right atrium. It is suggested that fixed-rate pacemakers may be contra-indicated and that sequential atrioventricular demand pacing is theoretically ideal.
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“The Medical Journal of Australia”
The Medical Journal of Australia · 1923 · 1.6K citations
Diseases of the Heart and Circulation
Postgraduate Medical Journal · 1957 · 802 citations
Clinical Spectrum of the Sick Sinus Syndrome
Joel J. Rubenstein, Charles L. Schulman, Peter M. Yurchak et al. · Circulation · 1972 · 439 citations · Full text
The Sick Sinus Syndrome in Atrial Disease
M. IRENÉ FERRER · JAMA · 1968 · 358 citations
Cardiac Conduction in Patients with Symptomatic Sinus Node Disease
Kenneth M. Rosen, Henry S. Loeb, M. Ziad Sinno et al. · Circulation · 1971 · 250 citations · Full text