First functionalization by metallation of the benzene moiety of quinazolines. Diazines XIX

Directed lithiation of aromatic tertiary amides: an evolving synthetic methodology for polysubstituted aromatics

Peter Beak, Victor Snieckus · Accounts of Chemical Research · 1982 · 427 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Syntheses of Heterocyclic Compounds Involving Aromatic Lithiation Reactions in the Key Step

N. S. Narasimhan, R. S. MALI · Synthesis · 1983 · 92 citations

Natural Sciences, Chemistry, Catalysis +6

Lithiation of 3-(Acylamino)-2-unsubstituted-, 3-(Acylamino)-2-ethyl-, and 3-(Acylamino)-2-propyl-4(3<i>H</i>)-quinazolinones:  Convenient Syntheses of More Complex Quinazolinones¹

Keith Smith, Gamal A. El‐Hiti, Mohamed F. Abdel‐Megeed et al. · The Journal of Organic Chemistry · 1996 · 62 citations

Natural Sciences, Chemistry, Green Chemistry +6

The selective metalation of 1-methoxynaphthalene in either the 2- or 8-position

D. A. Shirley, Chun Fong Cheng · Journal of Organometallic Chemistry · 1969 · 56 citations

Natural Sciences, Chemical Engineering, Chemistry +7

Quinazoline Derivatives.¹ I. The Synthesis of 4-(4'-Diethylamino-1'-methylbutyl-amino)-quinazoline (SN 11,534) and the Corresponding 2-Phenylquinazoline (SN 11,535)²

Margaret M. Endicott, Emily L. Wick, Marie L. Mercury et al. · Journal of the American Chemical Society · 1946 · 55 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7