Extraluminally applied acetylcholine and oxyhemoglobin on the release and action of EDRF

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Mechanobiology, Obligatory Role, Molecular Physiology +12

Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.

William Martin, G. Villani, D Jothianandan et al. · Journal of Pharmacology and Experimental Therapeutics · 1985 · 1.3K citations

Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor.

William Martin, Robert F. Furchgott, G. Villani et al. · Journal of Pharmacology and Experimental Therapeutics · 1986 · 373 citations

Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite

Carl A. Gruetter, Philip J. Kadowitz, Louis J. Ignarro · Canadian Journal of Physiology and Pharmacology · 1981 · 315 citations

Heterogeneity in mechanisms of bradykinin action in canine isolated blood vessels

Noboru Toda, Ka Bian, T Akiba et al. · European Journal of Pharmacology · 1987 · 67 citations

Blood Vessels, Molecular Physiology, Angiogenesis +8