Magnetic Nanocomposite Particles and Hollow Spheres Constructed by a Sequential Layering Approach

TLDR

Nanoengineered colloidal particles can serve as magnetically directed delivery systems or diagnostics. Composite core–shell particles were fabricated by layer‑by‑layer coating of polystyrene latices with alternating magnetite and polyelectrolyte layers, allowing nanoscale thickness control, and hollow magnetic spheres were produced by calcining these core–shell particles or by calcining polystyrene latices coated with silica and Fe₃O₄ multilayers. The multistep strategy successfully produced magnetic core–shell particles and hollow spheres with tunable dimensions, and transmission electron microscopy showed that increasing polyelectrolyte interlayers from one to three markedly improved multilayer growth, uniformity, and regularity.

Abstract

The fabrication of magnetic composite core−shell particles and hollow spheres with tailored dimensions and compositions has been accomplished by a multistep (layer-by-layer) strategy. Composite particles were prepared by coating submicrometer-sized anionic polystyrene (PS) latices with magnetite (Fe3O4) nanoparticle layers alternately adsorbed with polyelectrolyte from aqueous solution. The thickness of the deposited multilayers could be finely tuned with nanoscale precision, either by selection of the number of adsorption cycles performed or by the number of polyelectrolyte layers deposited between each nanoparticle layer (i.e., interlayer). As demonstrated by transmission electron microscopy, a marked improvement in the growth, uniformity, and regularity of the composite multilayers was achieved when the number of polyelectrolyte interlayers was increased from one [(poly(diallyldimethylammonium chloride) (PDADMAC)] to three [(PDADMAC/poly(styrenesulfonate) (PSS)/PDADMAC)]. Hollow, intact magnetic spheres were obtained by calcination of the core−shell particles at elevated temperature. Furthermore, composite hollow spheres were prepared by calcination of PS latices coated with multilayers of silica and Fe3O4 nanoparticles. These nanoengineered colloidal particles may potentially find applications as delivery systems, or in diagnostics, where the particles can be directed by application of an external magnetic field.