Treatment of Severe La Crosse Encephalitis With Intravenous Ribavirin Following Diagnosis by Brain Biopsy

Abstract

Experience and Reason| February 01 1997 Treatment of Severe La Crosse Encephalitis With Intravenous Ribavirin Following Diagnosis by Brain Biopsy James E. McJunkin, MD; James E. McJunkin, MD Search for other works by this author on: This Site PubMed Google Scholar Raheel Khan, MD; Raheel Khan, MD Search for other works by this author on: This Site PubMed Google Scholar Emily C. de los Reyes, MD; Emily C. de los Reyes, MD Search for other works by this author on: This Site PubMed Google Scholar Debra L. Parsons, MD; Debra L. Parsons, MD Search for other works by this author on: This Site PubMed Google Scholar Linda L. Minnich, SM(AAM); Linda L. Minnich, SM(AAM) Search for other works by this author on: This Site PubMed Google Scholar Rebecca G. Ashley, MT; Rebecca G. Ashley, MT Search for other works by this author on: This Site PubMed Google Scholar Theodore F. Tsai, MD Theodore F. Tsai, MD Search for other works by this author on: This Site PubMed Google Scholar Address correspondence to: James E. McJunkin, MD, Robert C. Byrd Health Sciences Center, 830 Pennsylvania Avenue, Suite 104, Charleston, WV 25302–3389. Pediatrics (1997) 99 (2): 261–267. https://doi.org/10.1542/peds.99.2.261 Article history Received: December 04 1995 Accepted: April 10 1996 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation James E. McJunkin, Raheel Khan, Emily C. de los Reyes, Debra L. Parsons, Linda L. Minnich, Rebecca G. Ashley, Theodore F. Tsai; Treatment of Severe La Crosse Encephalitis With Intravenous Ribavirin Following Diagnosis by Brain Biopsy. Pediatrics February 1997; 99 (2): 261–267. 10.1542/peds.99.2.261 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search toolbar search search input Search input auto suggest filter your search All PublicationsAll JournalsPediatricsHospital PediatricsPediatrics In ReviewNeoReviewsAAP Grand RoundsAAP NewsAll AAP Sites Search Advanced Search Topics: brain biopsy, la crosse encephalitis, ribavirin, encephalitis, herpes simplex, la crosse virus, immunoglobulin m, immunoglobulin g La Crosse virus is a mosquito-borne bunyavirus that has been neglected as a cause of pediatric central nervous system (CNS) infection. The disease recurs every summer in endemic foci in the midwestern and mid-Atlantic United States in areas forested with hardwood trees, which provide breeding sites for the treehole-dwelling mosquito vector, Aedes triseriatus.1 During hyperendemic years, the prevalence of disease in some of these areas can be remarkably high, exceeding that of bacterial meningitis.1 2 Clinical manifestations in symptomatic cases of La Crosse encephalitis (LE) tend to cluster into a mild form or a severe form of the disease.3-10 The usual clinical course (80% to 90%) is the mild form in which headache, fever, and vomiting frequently occur on days 1 to 3. Lethargy, behavioral changes, and/or brief seizures may occur on days 3 and 4, followed by improvement over a 7- to 8-day period. The... You do not currently have access to this content.