Concepedia

Mitochondrial Permeability Transition Pore Component Cyclophilin D Distinguishes Nigrostriatal Dopaminergic Death Paradigms in the MPTP Mouse Model of Parkinson's Disease

Bobby Thomas, Rebecca Banerjee, Natalia N. Starkova, Steven F. Zhang, Noel Y. Calingasan, Lichuan Yang, Elizabeth Wille, Beverly Lorenzo, Daniel Ho, M. Flint Beal,

Antioxidants and Redox Signaling · 2011 · 55 citations · 47 references

DOIFull text

Open access

Abstract

Our results suggest that CYPD deficiency distinguishes the modes of dopaminergic neurodegeneration in various regimens of MPTP-neurotoxicity.

References

47

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Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

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Vernice Jackson‐Lewis, Serge Przedborski · Nature Protocols · 2007 · 1.1K citations

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