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PROLONGATION OF CANINE RENAL HOMOGRAFT SURVIVAL BY ANTIMETABOLITES
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1963
Year
UrologyRenal Function6-Methyl MercaptopurineCanine Renal HomograftsMedicineChronic Kidney DiseaseBurroughs WellcomeDialysis TherapyPharmacotherapyPharmacologyRenal PharmacologyNephrologyKidney Research
Burroughs Wellcome 57-322 and 6-methyl mercaptopurine have prolonged survival of canine renal homografts. Urethan plus 6-azauracil achieved moderate prolongation, but cyclophosphamide and vinblastine sulfate were ineffective at the dosages studied.