Concepedia

Synthesis of cryptolepine analogues as potential bioreducible anticancer agents

Scott Seville, Roger M. Phillips, Steven D. Shnyder, Colin W. Wright

Bioorganic & Medicinal Chemistry · 2007 · 22 citations · 14 references

DOI

Concepts

References

14

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.

R D Traver, T. Horikoshi, Kathleen D. Danenberg et al. · PubMed · 1992 · 317 citations

, , +13

The DNA Intercalating Alkaloid Cryptolepine Interferes with Topoisomerase II and Inhibits Primarily DNA Synthesis in B16 Melanoma Cells

Karine Bonjean, M. C. De Pauw-Gillet, Marie Paule Defresne et al. · Biochemistry · 1998 · 211 citations

, , +17

Synthesis and Evaluation of Cryptolepine Analogues for Their Potential as New Antimalarial Agents

Colin W. Wright, Jonathan Addae-Kyereme, Anthony G. Breen et al. · Journal of Medicinal Chemistry · 2001 · 190 citations

, , +17

The antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sites

J. N. Lisgarten, Miquel Coll, José Portugal et al. · Nature Structural Biology · 2001 · 187 citations

, , +7