One-Pot Synthesis of Pentaalkyl 7-[(Alkylamino)carbonyl]-2-oxa-1-azabicyclo[3.2.0]hept-3-ene-3,4,5,6,7-pentacarboxylate

Abstract

Dialkyl acetylenedicarboxylates react with alkyl 2-nitroethanoates in the presence of alkyl isocyanides in a one-pot reaction to afford the title compounds in 78–90% yield.