WT1 Mutants Reveal SRPK1 to Be a Downstream Angiogenesis Target by Altering VEGF Splicing

Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer

Herbert I. Hurwitz, Louis Fehrenbacher, William Novotny et al. · New England Journal of Medicine · 2004 · 11K citations · Full text

Medicine, Oncology, Pharmacology +15

The Vascular Endothelial Growth Factor Family: Identification of a Fourth Molecular Species and Characterization of Alternative Splicing of RNA

Keith A. Houck, Napoleone Ferrara, Jane Winer et al. · Molecular Endocrinology · 1991 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Biology +11

The gene encoding the splicing factor SF2/ASF is a proto-oncogene

Rotem Karni, Elisa de Stanchina, Scott W. Lowe et al. · Nature Structural & Molecular Biology · 2007 · 937 citations

Medicine, Genetics, Molecular Biology +12

Alternative splicing and genomic structure of the Wilms tumor gene WT1.

Daniel A. Haber, Regina Sohn, Alan Buckler et al. · Proceedings of the National Academy of Sciences · 1991 · 626 citations

Life Sciences, Genetics, Molecular Genetics +15

VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma.

Tai-Gen Cui, Joanne M. Doughty, Marto Sugiono et al. · PubMed · 2002 · 556 citations

Medicine, Molecular Biology, Oncology +17