RELEASE OF PROSTAGLANDINS AFTER AMNIOTOMY IS NOT MEDIATED OXYTOCIN

Abstract

The rise in peripheral plasma levels of 13,14-dihydro-15-keto-prostaglandin F (PGFM) following amniotomy has now been shown to be maximal within five minutes of the procedure, and levels remain elevated for at least 30 minutes. There was no change in plasma oxytocin levels with amniotomy and therefore a local mechanism for prostaglandin release has been postulated.