Bioactivity-Directed Fractionation of Alkaloids from Some Amaryllidaceae Plants and Their Anticholinesterase Activity

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.9K citations

Life Sciences, Biochemistry, Pharmacology +14

A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease

Samantha Rogers, Martin R. Farlow, Rachelle S. Doody et al. · Neurology · 1998 · 1.6K citations

Medicine, Pharmacotherapy, Psychiatry +17

Oral Tetrahydroaminoacridine in Long-Term Treatment of Senile Dementia, Alzheimer Type

William K. Summers, Lawrence V. Majovski, Gary M. Marsh et al. · New England Journal of Medicine · 1986 · 1.2K citations

Medicine, Neurology, Pharmacology +15

A colorimetric method for determining low concentrations of mercaptans

George L. Ellman · Archives of Biochemistry and Biophysics · 1958 · 1.1K citations

Natural Sciences, Biochemistry, Chemistry +9

CHANGES IN BRAIN CHOLINESTERASES IN SENILE DEMENTIA OF ALZHEIMER TYPE

Elaine K. Perry, R. H. Perry, G. Blessed et al. · Neuropathology and Applied Neurobiology · 1978 · 555 citations

Life Sciences, Biochemistry, Neuroscience +17