Anesthesiology · 1971 · 75 citations · 0 references
Life SciencesPharmacologyPhysiologyPharmacodynamicsRespiratory PharmacotherapyVentilationGas ExchangeGas Exchange PhysiologyPulmonary PhysiologyRespiratory PathophysiologyRespiratory PharmacologyRespiratory PhysiologyCarbon DioxideHypoxic Ventilatory ResponsePulmonary Gas ExchangePulmonary Gas TransferRespiratory Gas ExchangeVentilatory Response To Hypercapnia
The effects of diazepam (0.14 mg/kg) on steady-state gas exchange were studied in 13 patients, and the responses to a carbon dioxide stimulus using a recently introduced rebreathing technique are described. There were significant increases in VD/VT and Paco2, and a decrease in VT. E and o2- were unc