Publication | Open Access

JAK/STAT but Not ERK1/ERK2 Pathway Mediates Interleukin (IL)-6/Soluble IL-6R Down-regulation of Type II Collagen, Aggrecan Core, and Link Protein Transcription in Articular Chondrocytes

InflammationRheumatologyCytokineMusculoskeletal ResearchAutoimmune DiseaseArticular ChondrocytesExtracellular MatrixImmunologyCartilage DegenerationChronic InflammationOsteoarthritisType Ii CollagenMedicineCell BiologyCell SignalingLink Protein TranscriptionJak-stat Signaling Pathway