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Total and Individual Kidney Function Assessment with Iodine-123 Ortho-iodohippurate
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1977
Year
HemodialysisUrologyRenal FunctionL-123 OihMedicineIodine Deficiency DisordersKidney FailureL-131 OihLaboratory MedicineIodine-123 Ortho-iodohippurateClinical ChemistryChronic Kidney DiseaseNuclear MedicineNephrologyRadiology
A simple and reliable method of preparing 123l o-iodohippurate (l-123 OIH) is described. The agent was used to evaluate renal function in 329 patients; its use results in significant dose reduction for those with obstruction, hypertension, or transplant. Images from l-123 OIH provide 2.4 times more detectable photons per mCi administered to the patient than images obtained from l-131 OIH. Diagnoses are expected to be more reliable with l-123 OIH due to the decreased random variation of each data point.