Mutations in the α1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia

Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes.

Val C. Sheffield, David R. Cox, Leonard S. Lerman et al. · Proceedings of the National Academy of Sciences · 1989 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

A primary acoustic startle circuit: lesion and stimulation studies

M. Davis, DS Gendelman, MD Tischler et al. · Journal of Neuroscience · 1982 · 971 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

[31] Detection and localization of single base changes by denaturing gradient gel electrophoresis

R Myers, Tom Maniatis, Leonard S. Lerman · Methods in enzymology on CD-ROM/Methods in enzymology · 1987 · 936 citations

Life Sciences, Biochemistry, Molecular Biology +10

The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors

Gabriele Grenningloh, Axel Rienitz, Bertram Schmitt et al. · Nature · 1987 · 731 citations

Life Sciences, Neurobiology, Neuroscience +14

Radiation Hybrid Mapping: A Somatic Cell Genetic Method for Constructing High-Resolution Maps of Mammalian Chromosomes

David R. Cox, Margit Burmeister, Edward Price et al. · Science · 1990 · 627 citations

Life Sciences, Genetics, Molecular Genetics +15