Toll-like Receptor 5 Agonist Protects Mice From Dermatitis and Oral Mucositis Caused by Local Radiation: Implications for Head-and-Neck Cancer Radiotherapy

Phase III Randomized Trial of Amifostine as a Radioprotector in Head and Neck Cancer

David M. Brizel, Todd H. Wasserman, Michael Henke et al. · Journal of Clinical Oncology · 2000 · 832 citations

Medicine, Oncology, Radiation Oncology +15

An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models

Lyudmila G. Burdelya, Vadim I. Krivokrysenko, Thomas C. Tallant et al. · Science · 2008 · 699 citations

Medicine, Oncology, Radiation Oncology +17

Toll-Like Receptor 5 Engagement Modulates Tumor Development and Growth in a Mouse Xenograft Model of Human Colon Cancer

Sang Hoon Rhee, Eunok Im, Charalabos Pothoulakis · Gastroenterology · 2008 · 179 citations · Full text

Life Sciences, Immunology, Oncology +16

The Stable Nitroxide Tempol Facilitates Salivary Gland Protection during Head and Neck Irradiation in a Mouse Model

Joseph M. Vitolo, Ana P. Cotrim, Anastasia L. Sowers et al. · Clinical Cancer Research · 2004 · 84 citations

Dentistry, Radiation Oncology, Radiation Protection +16

Amifostine Induces Antioxidant Enzymatic Activities in Normal Tissues and a Transplantable Tumor That Can Affect Radiation Response

David J. Grdina, Jeffrey S. Murley, Yasushi Kataoka et al. · International Journal of Radiation Oncology*Biology*Physics · 2009 · 40 citations · Full text

Medicine, Oncology, Radiation Oncology +16