A High-Mr Glycoprotein Fraction from Cow’s Milk Potent in Inhibiting Replication of Human Rotavirus<i>in Vitro</i>

Abstract

Rotavirus is the major cause of infectious diarrhea in infants and young children all over the world. We have found that a high-M(r) glycoprotein fraction from cow's milk is potent in inhibiting replication of human rotaviruses in vitro. Since the activity seems to be unique and specific, this fraction may be useful as a novel agent for treatment or prevention of rotavirus diarrhea.