Granulocytapheresis Is Useful as an Alternative Therapy in Patients with Steroid-refractory or -dependent Ulcerative Colitis

Abstract

The findings of this study suggest that GCAP may be a useful alternative therapy for patients with moderate steroid-refractory or -dependent UC, although cyclosporin A or colectomy is necessary in patients with severe UC. GCAP may also be useful for avoiding re-administration of steroids at the time of relapse. Randomized, controlled clinical trials are needed to confirm these findings.