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Organocatalytic Phosphorylation of Alcohols Using Pyridine-N-oxide

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2015

Year

Abstract

Phosphorylation of alcohols by phosphoryl chlorides catalysed by pyridine-<i>N</i>-oxide is reported. The utility of this method is demonstrated through phosphorylation of primary, secondary and a tertiary alcohol as well as phenols under mild reaction conditions and with low catalyst loading (5 mol%).