Noradrenaline enhances angiotensin II responses via p38 MAPK activation after hypoxia/re‐oxygenation in renal interlobar arteries

Abstract

The results suggest an interaction of NE and hypoxia in enhancing vasoreactivity, which may be important for the pathogenesis of AKI. The effect of NE+hypoxia in ILA is mediated by several adrenergic receptors and requires the p38 MAPK activation.