Intravenous Sildenafil as a Preconditioning Drug Against Hemodynamic Consequences of Warm Ischemia-Reperfusion on the Kidney

Abstract

The effect of intravenous sildenafil as a preemptive drug against the hemodynamic effects of renal ischemia-reperfusion is dose dependent. The 0.7 mg/kg dose significantly increased reperfusion renal vascular flow with a small decrease in arterial pressure compared to the 1.4 mg/kg dose.