Schizophrenia and Schizophrenia-Spectrum Personality Disorders in the First-Degree Relatives of Children With Schizophrenia

Abstract

The psychiatric disorders that do and do not aggregate in the parents of COS probands are remarkably similar to the disorders that do and do not aggregate in the parents of adults with schizophrenia in modern family studies. These findings provide compelling support for the hypothesis of etiological continuity between COS and AOS.