Journal of the American Chemical Society · 2011 · 207 citations · 74 references
Natural SciencesChemistryMedicinal ChemistryCatalysisOrganic ChemistryCatalytic MechanismsHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsOrganic SynthesisRedox ReactionsAnnulation ReactionsAzepine ChemistryIndole ChemistryIndole DerivativesIndole SynthesisRing-forming Reactions
Aminobenzaldehydes react with indoles in an unprecedented cascade reaction. This acid-catalyzed redox-neutral annulation proceeds via a condensation/1,5-hydride shift/ring-closure sequence. Polycyclic azepinoindoles and related compounds are obtained in a single step with good to excellent yields.
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C-H Bond Functionalization in Complex Organic Synthesis
Kamil Godula, Dalibor Sameš · Science · 2006 · 2.1K citations
Robert G. Bergman · Nature · 2007 · 1.5K citations