Control of the Initiation of DNA Synthesis in 3T3 Cells: Serum Factors

Robert W. Holley, Josephine A. Kiernan

Proceedings of the National Academy of Sciences · 1974 · 182 citations · 16 references

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Abstract

The initiation of DNA synthesis in 3T3 cells can be controlled by a variety of different factors. Cells that are quiescent because of limited serum initiate DNA synthesis in response to the fibroblast growth factor of Gospodarowicz, to insulin, and to dexamethasone, as well as to other, unidentified biological materials. Interactions are seen between the effects of different factors.

References

16