Expression of Matrix Metalloproteinase 2 and 9 in Experimentally Wounded Canine Corneas and Spontaneous Chronic Corneal Epithelial Defects

Abstract

The dog exhibits similar MMP expression during corneal wound healing to that of other species. The lack of significant difference in MMP expression between SCCED and chronic wounds suggest that MMP 2 and 9 are not involved in the pathophysiology of SCCED and are more likely altered secondary to a chronic epithelial defect.