Antagonism of d-Tubocurarine- and Pancuronium-induced Neuromuscular Blockades by Pyridostigmine in Man

Abstract

Pyridostigmine was administered to 30 unpremedicated adult surgical patients anesthetized with nitrous oxide and halothane to antagonize neuromuscular blockade by d-tubocurarine (dTc) or pancuronium. The mean doses of pyridostigmine necessary for 50 per cent recovery of depressed twitch height and f