Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis

Michael J. Elliott, Ravinder N. Maini, Marc Feldmann et al. · The Lancet · 1994 · 1.7K citations

Medicine, Clinical Sciences, Immunology +15

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

Michael J. Elliott, Ravinder N. Maini, Marc Feldmann et al. · Arthritis & Rheumatism · 1993 · 1K citations

Life Sciences, Clinical Sciences, Immunology +15

Construction and initial characterization of a mouse-human chimeric anti-TNF antibody

David Knight, Han Trinh, Junming Le et al. · Molecular Immunology · 1993 · 710 citations

Pharmacy, Immunology, Molecular Biology +14

Humanised monoclonal antibody therapy for rheumatoid arthritis

John D. Isaacs, G Hale, Stephen Cobbold et al. · The Lancet · 1992 · 312 citations

Pharmacy, Immunology, Pharmacotherapy +14

Analysis of improvement in individual rheumatoid arthritis patients treated with disease‐modifying antirheumatic drugs, based on the findings in patients treated with placebo

Harold E. Paulus, Marlene J. Egger, John Ward et al. · Arthritis & Rheumatism · 1990 · 287 citations

Medicine, Internal Medicine, Pharmacotherapy +14