Quantitative analysis of immunoglobulin E reactivity profiles in patients allergic or sensitized to natural rubber latex (<i>Hevea brasiliensis</i>)

Abstract

Hev b 1, 2, 5, 6.01 and 13 were identified as the major Hev b allergens and they should be present in standardized latex extracts and in vitro allergosorbents. CCDs are only of minor relevance in patients with clinical relevant latex allergy. Component-resolved diagnostic analyses for latex allergy set the stage for an allergen-directed immunotherapy strategy.