Concepedia

Polyamine derivatives as inhibitors of trypanothione reductase and assessment of their trypanocidal activities

Mary C. O’Sullivan, Qibing Zhou, Zhili Li, Timothy B. Durham, Donna Rattendi, Schennella Lane, Cyrus J. Bacchi

Bioorganic & Medicinal Chemistry · 1997 · 52 citations · 32 references

DOI

Concepts

References

32

Trypanothione: A Novel Bis(glutathionyl)spermidine Cofactor for Glutathione Reductase in Trypanosomatids

Alan H. Fairlamb, Peter Blackburn, Peter Ulrich et al. · Science · 1985 · 678 citations

, , +15

Purification and characterization of trypanothione reductase from Crithidia fasciculata, a new member of the family of disulfide-containing flavoprotein reductases

Spencer L. Shames, Alan H. Fairlamb, Anthony Cerami et al. · Biochemistry · 1986 · 271 citations

, , +7

Disulfide‐Reductase Inhibitors as Chemotherapeutic Agents: The Design of Drugs for Trypanosomiasis and Malaria

R. Heiner Schirmer, Joachim G. Müller, R. Luise Krauth‐Siegel · Angewandte Chemie International Edition in English · 1995 · 214 citations

, , +17

Rationally designed selective inhibitors of trypanothione reductase. Phenothiazines and related tricyclics as lead structures

Timothy J. Benson, James H. McKie, J. Garforth et al. · Biochemical Journal · 1992 · 154 citations · Full text

, , +15

Trypanothione reductase from <i>Trypanosoma cruzi</i>

Maria C. JOCKERS‐SCHERÜBL, R. Heiner Schirmer, R. Luise Krauth‐Siegel · European Journal of Biochemistry · 1989 · 150 citations · Full text

, , +15