Granulocyte Macrophage Colony-Stimulating Factor Improves Survival in Two Models of Gut-Derived Sepsis by Improving Gut Barrier Function and Modulating Bacterial Clearance

Abstract

The ability of rmGM-CSF to improve gut barrier function and enhance killing of translocated organisms after burn injury-induced gut origin sepsis was associated with improved outcome. Granulocyte macrophage colony-stimulating factor also improved survival after CLP.