Domains of Pit-1 required for transcriptional synergy with GATA-2 on the TSHβ gene

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

Donald B. Smith, Kevin S. Johnson · Gene · 1988 · 6K citations

Life Sciences, Biochemistry, Molecular Biology +12

High-efficiency transformation of mammalian cells by plasmid DNA.

C Chen, Hiroto Okayama · Molecular and Cellular Biology · 1987 · 5.3K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +13

Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1

Sen Li, E. Bryan Crenshaw, Elizabeth J. Rawson et al. · Nature · 1990 · 1.2K citations

Medicine, Genetics, Molecular Genetics +16

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

Holly A. Ingraham, Ruoping Chen, Harry J. Mangalam et al. · Cell · 1988 · 1K citations

Life Sciences, Genetics, Molecular Biology +14