Radiation Research · 1983 · 27 citations · 17 references
MedicineOncologyToxicologyRadiation DosimetryRadiation ProtectionRadiobiologyBiological Effects Of RadiationFractionation EffectsRadiation HealthRadiation Risk AssessmentRadiation TherapyRadiation ToxicityFractionated Exposure EffectsGamma Irradiation EffectsGamma Radiation AssessmentKidney DiseasesRadiation Dose EffectsRadiation Fractionation EffectsRadiation ToxicologyRadiobiological Response
BALB/c male mice (12 weeks old) were exposed to a single or fractionated exposure of 137Cs gamma rays. The fractionated dose was split into 10 equal doses delivered at an interval of 1 day. The causes and possible causes of spontaneous death were ascertained by autopsy and histological examination, and the data were treated by competing risk analysis. Life shortening followed a linear dose dependency and was about the same for fractionated (38.1 +/- 3.1 days/Gy) as for single (46.2 +/- 4.3 days/Gy) exposure. Death from tumor disease was enhanced and that from nonstochastic lung and kidney diseases was reduced after fractionated compared to single exposure.
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Henry S. Kaplan, Mary Bomberger Brown · JNCI Journal of the National Cancer Institute · 1952 · 232 citations
A comparison of the induction of myeloid and lymphoid leukemias in x-radiated RF mice.
A. C. Upton, Florian Wolff, J. Fürth et al. · PubMed · 1958 · 123 citations